Yeast vs. Parkinson’s Disease: How Lviv Scientists Search for Remedies

We have sneaked into the laboratory which searches for causes and medicine for Parkinson’s disease. Molecular biologist Lesia Romanyshyn told us why the rats on the photo shine green, how to distinguish GMO from not GMO, and how to treat Parkinson’s disease with the help of traditional yeast. Also, Lesia told us what in general molecular biologists in the laboratories of our city deal with.

But first let’s make clear what Parkinson’s disease is and what causes it:

Parkinson’s disease is connected with my favourite neuromediator, dopamine. Dopamine enables us to feel happiness, euphoria and satisfaction. Also, it controls pain. Exactly it is involved in love: brain of a person, who is in love, begins producing this neuromediator rapidly.

Also, this neuromediator is responsible for the movement, that’s why it is produced in certain cells of the brain which control muscular activity. Dopamine is a vital ingredient, disfunction of which causes poor health and very serious disorders of motor and muscular activity, such as Parkinson’s disease.

Parkinson’s disease has two forms: sporadic and hereditary. Hereditary form is caused by mutations in 5 (according to some data, can be more) genes, one of which is a gene SNCA, which encodes protein alpha-synuclein. This protein provides moving of dopamine along neurons.

In short: dopamine deficiency causes Parkinsonism, and protein alpha-synuclein, to be exact, its irregular forms may cause dopamine deficiency.


Photo: Julia Low

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